Without pain and without symptoms: how Rob discovered his cancer

Rob, a resident of England, felt perfectly healthy until the 'Galleri' blood test—a screening tool for early cancer detection—twice flagged a potential issue. Subsequent examinations revealed stage 1 cancer at the base of his tongue. How does this test work, who is it for, and how can it be accessed in Israel?

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Without pain and without symptoms: how Rob discovered his cancer
Photo: Mako / צילום: GRAIL

The first time Rob received the phone call, he was at work. A few weeks earlier, he had provided a blood sample as part of the NHS-Galleri study, thinking little of it. Rob felt fine, worked as usual, and had no symptoms. Then came the unexpected news: "They told me a signal indicating cancer had been detected," he recalls. While the 'Galleri' test is not a diagnostic tool on its own, it can detect cancer signals; in his case, it pointed to the head and neck area.

Robert, a carpenter from Shropshire, joined the study at age 55, partly because both his parents had passed away from cancer. "A simple blood test—why wouldn't I do it?" he says. Even when the result came back, Rob felt healthy, and his specialist was initially surprised to see him given the complete absence of symptoms.

Initial MRI and pan-endoscopy scans were inconclusive. However, a year later, a second blood sample triggered the same alert. This time, a targeted biopsy confirmed squamous cell carcinoma at the base of the tongue—a stage 1, very early-stage cancer. "The test didn't replace the doctors, but it pointed them in the right direction," Rob notes.


What is the 'Galleri' test?

'Galleri' is an MCED (Multi-Cancer Early Detection) test designed to identify over 50 types of cancer from a single blood sample. It is intended to complement, not replace, standard screening tests like mammograms or colonoscopies.

Rob's story highlights the life-saving potential of early detection. Without the test, the disease might have progressed to a much more advanced stage. Following radiation and chemotherapy in early 2025, Rob received the news he had been waiting for: he was cancer-free. Today, he is back to work and his daily routine.

Study Findings

Data presented at the ASCO 2026 conference, involving over 142,000 participants, showed significant promise. While the primary goal of reducing late-stage mortality for 12 specific cancer types was not fully met, researchers observed a 26% decrease in stage 4 diagnoses by the third round of testing. Furthermore, adding 'Galleri' to standard screening programs increased the detection of stage 1 and 2 cancers by 16%.

In Israel, the 'Galleri' test is available through Oncotest. It is recommended for individuals aged 50 and over, those with a family history of cancer, carriers of high-risk genetic mutations, and cancer survivors.

For more information about the test >> click here.

To order the test >> click here.

Sponsored by Oncotest.

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